A research published in the Lancet and funded by the British Health Foundation has bet on cardiovascular magnetic resonance (CMR) for detecting coronary artery disease (CAD). They have shown their thumbs down for its other option, single-photon emission computed tomography (SPECT) for many reasons.
One of the major reasons is SPECT increases the risk of cancer. The Lead Researcher, John Greenwood, MD, of the Leeds General Infirmary and team said their findings have shown that CMR is better option to check if one has CAD or not. People should refrain from opting it’s another option, SPECT.
In order to reach at the above point, they enrolled as many as 752 volunteers in two hospitals and followed them from March 2006 to August 2009.
In their trial, CE-MARK they asked heart patients to undergo following procedures, MRI, SPECT, and invasive x-ray coronary angiography.
The experiment had certain parameters on which these procedures were judged. Those assessing factors were sensitivity, specificity, and predictive value which could be negative as well as positive.
In every aspect MRI outperformed SPECT. When it came to sensitivity, MRI showed 86.5% accuracy while SPECT showed very less in comparison to it, 66.5%.
Again in specificity MRI was ahead. MRI showed 83.4% specificity and SPECT showed 82.6%. Last came, predictive value where MRI showed 77.2% value and SPECT showed 79.1% value.
Least affective was coronary angiography which showed only 39% coronary heart disease among the enrolled participants.
Greenwood said, "This trial has shown that, in a large population with suspected angina pectoris, CMR is an alternative to SPECT for the detection of clinically significant coronary heart disease, with better sensitivity and negative predictive values”.
This research has suggested that if people want to be more assured about their coronary heart disease report than they should opt for cardiovascular MRI than SPECT.
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