Cancers killed by soil bacteria

Soil-bacteriaNow cancer drugs can be delivered into tumors by a bacterium found in soil.

Due to lack of oxygen, within tumors, there can be growth of spores of the Clostridium sporogenes bacterium.

In an attempt to make a cancer drug active, an enzyme has been engineered genetically by UK and Dutch scientists.

According to experts this will still take a while to figure out the benefits of this work.

The spores are unable to grow at places where oxygen is there and only solid tumours enable them to grow like breast, brain and prostate tumours.

For several years now, about decades, the possibilities of clostridium ‘vectors’ to deliver cancer drugs are being investigated by researchers.

A better version of an enzyme into C. sporogenes was engineered by scientists from the University of Nottingham and Maastricht University.

There were animal tests carried out in which it was seen that when a drug is triggered by this enzyme, it becomes active once injected into the bloodstream.

The tumour cells are then killed by this that are present in its vicinity.

Professor Nigel Minton, who led the research, said, “Clostridia are an ancient group of bacteria that evolved on the planet before it had an oxygen-rich atmosphere and so they thrive in low oxygen conditions.”

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