Researchers Discover New Type of Prostate Cancer
Researchers at the Weill Cornell Medical College, the Broad Institute of MIT and Harvard and the Dana-Farber Cancer Institute have uncovered a distinct molecular subtype of prostate cancer, which according to them is prevalent among 15% of the patients with the disease. These mutations that they discovered are in the SPOP ('S-pop') gene and have been found in numerous patient tumors.
The researchers also claimed that this type of mutation is unique to prostate cancer and by targeting this mutation, new class of cancer diagnosis and treatment can be achieved. Due to the change in the way cells tags proteins for degradation, there is an accumulation of dangerous molecules, which drives the growth of cancer.
In the recent times there have been an array of discoveries of other genes linked to prostate cancer and this add to that tally. Overall, this all would accumulate to paint a comprehensive picture of how genetic alterations contribute to prostate cancer. According to Mark A. Rubin, Professor of Oncology in Pathology and vice chair for experimental pathology at Weill Cornell Medical College, "This study, tells us that prostate cancer is not just one disease. We have found two main pathways for prostate cancer to develop and this opens the door to development of specialized diagnostic tools and treatments".
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