Gene Behind Muscle Mass Regulation Detected, Claims Study

HulkThe study, which has been published in the Federation of American Societies for Experimental Biology (FASEB Journal), has claimed of identifying a novel mechanism by which muscle mass can be increased.

The study seems to be quite promising for the conditions that reduce muscle mass, like muscular dystrophy, Type 2 diabetes and injuries related to muscle inflammation. Lead researcher Dr. Lowenna Holt, who has been associated with the Garvan Institute of Medical Research, Sydney, was of the view that the gene known as Grb10, nicknamed as ‘Hulk’ protein has pivotal role to play in alterations being caused in muscles.

In order to reach at the above given result, the study researchers carried out a study on two groups of mice. One of the groups was muscular, as it has having problem in the Grb10 gene. However, the other group was functional and there was no problem in their normal muscles.

After assessing both the groups, it was revealed that alterations in the gene are caused during prenatal stage. The gene is responsible for altering the muscle growth as well as help in healing process.

"By identifying a novel mechanism regulating muscle development, our work has revealed potential new strategies to increase muscle mass”, said Holt.