Bridge between the Genetic Mutation and Migraines

Bridge between the Genetic Mutation and MigrainesLatest research conducted by the researches from the University of California, San Francisco has discovered a genetic mutation that is associated to migraines.

The mutations occur in a gene which is termed as casein kinase I delta (CKIdelta). The chief researcher of the study, Louis J. Ptacek said that it is for the first time that the researchers have connected a genetic mutation to the usual migraines.

He said that it is their initial sight into a black box that had not been understood up till now. The lead researcher is an investigator at the Howard Hughes Medical Institute at the University of California, San Francisco.

It has been witnessed that near about 30 million Americans have suffered from migraines. However, the cause of the same remains an unsolved mystery. Migraines are usually characterized by intense, throbbing head pain and are usually escorted by an aura, sensitivity to light and/or nausea.

The gene was determined by the researchers after having a detail sight into the genetics of two families with a background of migraines. They revealed that a large fragment of the migraine sufferers either had the mutated gene or belong to the parents who carried the mutated gene.

The research got published in the Journal Science Translational Medicine. It was financially funded by the A. P. Giannini Foundation, the Migraine Research Foundation, the U. S. Department of Defense and the Sandler Neurogenetic Fund.