Gene based blood test worked test may let transplants patients skip biopsies

biopsiesAccording U. S researchers said on Thursday, a gene based blood tests worked as well as a surgical procedure used to check for signs of rejection in patients with heart transplants. Typically through a procedure called an endomyocardinal biopsy, in which doctors insert a tube into a vein in the neck and into the heart, where tiny bits of tissue are collected and tested. 600 patients’ results of the team compared who were randomly assigned either to have a biopsy or to have an echocardiogram and the Allomap Test.

Dr. Michael Pham, a clinical assistant professor of cardiovascular medicine at Stanford and a leader of the study, “I think it will cause a paradigm shift in the way we look at monitoring for rejection,” Dr. Hannah Valentine of Stand ford University, who designed the study to determine whether it was safe to reduce the number of necessary biopsies by using the blood test said , “This represents a major step forward in the way we manage a patient after heart transplants because we can now safely reduce the numbers of heart biopsies,".

The study was to be presented in Chicago on Thursday at the annual meeting of the International Society for Heart and Lung Transplantation and was published online by the New England Journal of Medicine. It may be noted that the study involved 602 patients at 13 American transplant centers who had a transplant from six months to five earlier.

 

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