Fracture risk possible from heartburn drugs

fdaThe Food and Drug Administration warned that the risk of getting a spine, hip and wrist fracture might be there by taking some heartburn medications with long-term use.

Gastroesophageal reflux disease are treated by proton pump inhibitors. These PPIs are also used for the treatment of small intestine and stomach and ulcers and inflammation of the esophagus, along with frequent heartburn.

On Tuesday in a statement the FDA said that the product labeling will be changed to describe the possible increased risk.

Dr Joyce Korvick, deputy director for safety in FDA's Division of Gastroenterology Products said, "Epidemiology studies suggest a possible increased risk of bone fractures with the use of proton pump inhibitors for one year or longer, or at high doses."

The FDA's warning about revised labeling is prompted by the various studies that reported an increased risk of spine, wrist, and hip fractures in people using proton pump inhibitors.