For diabetes lower glycaemic cut-off

For diabetes lower glycaemic cut-offAccording to new research correlating glycaemic control with changes on retinal photos in more than 44,000 individuals it has been concluded that the threshold for a diabetes diagnosis should be reduced to a fasting plasma glucose of 6.5 mmol/L or an HbA1c of 6.5 per cent.

From nine studies in five countries, the DETECT-2 Collaboration used information. Professor Stephen Colagiuri from the University of Sydney was the lead author of its recent report in Diabetes Care.

The researchers noted that there was an increase in retinopathy as the current cut-points for diabetes were based largely on the glycaemic levels at which there were risks of microvascular complications.

However, subsequent studies had been inconsistent as there were limitations in original epidemiological datasets used as the basis for the definition.

Professor Colagiuri and his colleagues said, “Our study is the largest to examine this association and provides the statistical power for a more detailed and precise examination of glycaemic thresholds for diabetes-specific retinopathy.”

To disease of moderate to severe severity DETECT-2 restricted its definition of retinopathy and mild diseases were excluded.

There was keenness seen in a research group based at the University of Western Australia to screen diabetic patients for retinopathy and they found that Australian optometrists are keen but when treatable changes are detected are slow to refer them to ophthalmologists.

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